Environmental Arginine Controls Multinuclear Giant Cell Metabolism and Formation
Julia S Brunner , Loan Vulliard , Melanie Hofmann , Markus Kieler , Alexander Lercher, Andrea Vogel , Marion Russier , Johanna B Brüggenthies , Martina Kerndl , Victoria Saferding , Birgit Niederreiter , Alexandra Junza , Annika Frauenstein , Carina Scholtysek , Yohei Mikami , Kristaps Klavins , Gerhard Krönke , Andreas Bergthaler , John J O’Shea , Thomas Weichhart , Felix Meissner , Josef S Smolen , Paul Cheng , Oscar Yanes , Jörg Menche , Peter J Murray , Omar Sharif , Stephan Blüml , Gernot Schabbauer Nat Commun. 2020 Jan 22;11(1):431. DOI: 10.1038/s41467-020-14285-1 ************************************************************
Chromatin mapping and single-cell immune profiling define the temporal dynamics of ibrutinib response in CLL.
Rendeiro AF, Krausgruber T, Fortelny N, Zhao F, Penz T, Farlik M, Schuster LC, Nemc A, Tasnády S, Réti M, Mátrai Z, Alpár D, Bödör C, Schmidl C, Bock C. Nat Commun. 2020 Jan 29;11(1):577. doi: 10.1038/s41467-019-14081-6. PMID: 31996669
************************************************************
Transcranial Pulse Stimulation with Ultrasound in Alzheimer’s Disease-A New Navigated Focal Brain Therapy.
Beisteiner R, Matt E, Fan C, Baldysiak H, Schönfeld M, Philippi Novak T, Amini A, Aslan T, Reinecke R, Lehrner J, Weber A, Reime U, Goldenstedt C, Marlinghaus E, Hallett M, Lohse-Busch H. Adv Sci (Weinh). 2019 Dec 23;7(3):1902583. doi: 10.1002/advs.201902583. eCollection 2020 Feb. PMID: 32042569
************************************************************
Variants in ABCB4 (MDR3) across the spectrum of cholestatic liver diseases in adults.
Stättermayer AF, Halilbasic E, Wrba F, Ferenci P, Trauner M. J Hepatol. 2020 May 3:S0168-8278(20)30280-4. doi: 10.1016/j.jhep.2020.04.036. Online ahead of print. PMID: 32376413
************************************************************
TASL is the SLC15A4-associated adaptor for IRF5 activation by TLR7-9.
Heinz LX, Lee J, Kapoor U, Kartnig F, Sedlyarov V, Papakostas K, César-Razquin A, Essletzbichler P, Goldmann U, Stefanovic A, Bigenzahn JW, Scorzoni S, Pizzagalli MD, Bensimon A, Müller AC, King FJ, Li J, Girardi E, Mbow ML, Whitehurst CE, Rebsamen M, Superti-Furga G. Nature. 2020 May;581(7808):316-322. doi: 10.1038/s41586-020-2282-0. Epub 2020 May 13. PMID: 32433612
************************************************************
Ropeginterferon alfa-2b versus standard therapy for polycythaemia vera (PROUD-PV and CONTINUATION-PV): a randomised, non-inferiority, phase 3 trial and its extension study.
Gisslinger H, Klade C, Georgiev P, Krochmalczyk D, Gercheva-Kyuchukova L, Egyed M, Rossiev V, Dulicek P, Illes A, Pylypenko H, Sivcheva L, Mayer J, Yablokova V, Krejcy K, Grohmann-Izay B, Hasselbalch HC, Kralovics R, Kiladjian JJ; PROUD-PV Study Group. Lancet Haematol. 2020 Mar;7(3):e196-e208. doi: 10.1016/S2352-3026(19)30236-4. Epub 2020 Jan 31. PMID: 32014125
************************************************************
Microvascular Disease in Chronic Thromboembolic Pulmonary Hypertension: Hemodynamic Phenotyping and Histomorphometric Assessment.
Gerges C, Gerges M, Friewald R, Fesler P, Dorfmüller P, Sharma S, Karlocai K, Skoro-Sajer N, Jakowitsch J, Moser B, Taghavi S, Klepetko W, Lang IM. Circulation. 2020 Feb 4;141(5):376-386. doi: 10.1161/CIRCULATIONAHA.119.041515. Epub 2020 Jan 3. PMID: 31896275
